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这个问题，如有可能你应当先把大的控件停靠在窗体的某部分，其他的控件用form的resize事件触发控件宽高的数值或控件位置坐标的数值。例：
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Private Sub Form1_Resize(ByVal sender As Object, ByVal e As System.EventArgs) Handles Me.Resize
Dim pLabel1, pTextBox1, pButton1 As New Point
pLabel1.X = CInt(Me.Width / 7)
pLabel1.Y = CInt(Me.Height / 8) + 4
pTextBox1.X = CInt(Me.Width / 5)
pTextBox1.Y = CInt(Me.Height / 8)
pButton1.X = CInt(Me.Width / 3)
pButton1.Y = CInt(Me.Height / 8) - 1
Me.Label1.Location = pLabel1
Me.TextBox1.Location = pTextBox1
Me.Button1.Location = pButton1
End Sub
以上只是改变了控件的位置，如需改变控件的大小，重新定义计算控件的size属性
.Top 和 .Left
.Top 是距离屏幕顶端的距离,也就是Y坐标
.Left 是距离屏幕左边的距离，也就是X坐标
例如
Private Sub Form_Load()
With Me
.Top = 0
.Left = 0
End With
End Sub
把自己的位置调到最左上角
建立新的form，加入一个timer，interval设为100
Option Explicit
Private Declare Function GetCursorPos Lib "user32" (lpPoint As POINTAPI) As Long
Private Type POINTAPI
X As Long
Y As Long
End Type
Dim p As POINTAPI
Private Declare Function SetWindowPos Lib "user32" (ByVal hwnd As Long, ByVal hWndInsertAfter As Long, ByVal X As Long, ByVal Y As Long, ByVal cx As Long, ByVal cy As Long, ByVal wFlags As Long) As Long
Private Const HWND_TOPMOST = -1
Private Const SWP_NOMOVE = H2
Private Const SWP_NOSIZE = H1
Private Sub Form_Load()
SetWindowPos Me.hwnd, HWND_TOPMOST, 0, 0, 0, 0, SWP_NOMOVE Or SWP_NOSIZE '加载窗口是指定窗口在最顶层
Timer1.Enabled = True
End Sub
Private Sub Timer1_Timer()
On Error Resume Next
GetCursorPos p
If Me.Top = 0 Then 'form1 is not hide and form1's top is 0
'hide form
If p.Y Me.Height / 15 + Me.Top / 15 Or p.X Me.Width / 15 + Me.Left / 15 Or p.X Me.Left / 15 Then 'mouse is not over form1
Me.Top = 0 - Me.Height + 50
End If
'show form
If p.X Me.Left / 15 And p.X Me.Left / 15 + Me.Width / 15 And p.Y 3 Then 'mouse is over form
Me.Top = 0
End If
End If
If Me.Left = 0 Then ''form1 is not hide form1's left is 0
'hide form
If p.Y Me.Height / 15 + Me.Top / 15 Or p.Y Me.Top / 15 Or p.X Me.Width / 15 + Me.Left / 15 Then 'mouse is not over form1
Me.Left = 0 - Me.Width + 50
End If
'show form
If p.X 3 And p.Y Me.Top / 15 And p.Y Me.Height / 15 + Me.Top / 15 Then 'mouse is over form
Me.Left = 0
End If
End If
If Me.Left = Screen.Width - Me.Width Then
'hide form
If p.Y Me.Height / 15 + Me.Top / 15 Or p.Y Me.Top / 15 Or p.X Me.Left / 15 Then 'mouse is not over form1
Me.Left = Screen.Width - 50
End If
'show form
If p.X Screen.Width / 15 - 3 And p.Y Me.Top / 15 And p.Y Me.Height / 15 + Me.Top / 15 Then 'mouse is over form
Me.Left = Screen.Width - Me.Width
End If
End If
End Sub
本质是一个不规则形状的窗体，把窗体的 TopMost 属性设为 True 即可。